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HDL sjunker.


lillamy
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Har tagit kolesterolprover, HDL har sjunkit till 1,6 från 2,01.Har ätit lchf sedan januari.

Kan ngn kunnig tolka mina värden?

Tack på förhand.

 

 

Mars 2013

 

Socker 5,0

LDL 5,1

Total kolesterol 7,8

HDL 1,6

TRIG. 0,84

 

Nov. 2011

 

Socker 5,4

LDL 5.0 

Totala kolestrol   7.6  

HDL 2.01 

Trig. 1.11 

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"Discordance
Discordance is when there is a difference between LDL-C and LDL-P. If LDL-C is high and LDL-P is low, there is discordance. If LDL-C is low and LDL-P is high, there is discordance. If both are low or both high, there is no discordance. Studies have indicated that if there is discordance between LDL-C and LDL-P, cardiovascular disease risk tracks more closely with LDL-P than LDL-C. Specifically, when a patient with low LDL-C has a level of LDL-P that is not equally low, there is higher “residual” risk. This may help explain the high number of cardiovascular events that occur in patients with normal or low levels of LDL-C.
An analysis of “Get With the Guidelines” data published in 2009 studied almost 137 thousand patients with an acute coronary event. Almost half of those had admission LDL levels <100 mg/dL (2.6 mmol/L). Thus, LDL-C does not seem to be predicting risk in these patients. However, low HDL-C and elevated TG was common among these patients. Low HDL-C and high TG is generally associated with higher LDL-P.
Among discordant patients in the Framingham Offspring Study the group with the highest risk for future cardiovascular events had high LDL-P and low LDL-C, while the group with the lowest risk had low LDL-P but higher LDL-C.
Many patients with the metabolic syndrome or type-2 diabetes have the type of discordance where LDL-P is elevated but LDL-C may be close to normal. In these individuals, measurements of LDL-C may underestimate cardiovascular risk. Measurements of ApoB or LDL-P may therefore be helpful in these individuals.
Discordance may be an important clinical phenomenon. Sometimes the question of medical therapy in primary prevention arises when there is intermediate risk, based on LDL-C. In these cases a low LDL-P level might help to confirm that the risk is indeed low, which might justify avoiding statin therapy.
Statins tend to lower LDL-C more than LDL-P. Many individuals who reach the target for LDL-C with statins, may still have raised LDL-P. This may indicate residual risk despite what is generally defined as adequate treatment."

 

"Effect of therapies

In general, most methods that lower LDL-C have some ability to lower LDL-P. However, there are some differences. Much has been written about how to lower LDL-C. Most doctors will recommend eating less fat and cholesterol from meat and dairy products. Statin therapy significantly lowers LDL-C. Therapies may affect LDL-P differently. Interventions that will lower LDL-C more than LDL-P include statins, estrogen replacement therapy, some antiretrovirals, and a low-fat, high-carbohydrate diet. Interventions that lower LDL-P more than LDL-C include fibrates, niacin, pioglitazone, omega-3 fatty acids, exercise and Mediterranean and low carbohydrate diets. Although statins lower LDL-P, they may leave a significant number of patients above the LDL-P target.
Patients with high levels of triglycerides and low HDL-C are likely to have high LDL-P despite normal or low LDL-C. Such a lipid profile is typical for individuals with the metabolic syndrome. Studies indicate that these patients may benefit most from low carbohydrate diets and that carbohydrate restriction reduces LDL-P.
LDL-P is not generally used in Europe to assess cardiovascular risk. So far, these measurements have primarily been performed in the United States. Clinical guidelines in Europe still recommend measurements of LDL-C to assess risk. Furthermore, LDL-C is still recommended to assess the effect of statin therapy. However, due to the fact that LDL-C is only a surrogate marker of the availability of atherogenic lipoproteins, its use may be of limited value. Measurements of LDL-P and ApoB are better predictors of cardiovascular risk and provide a better reflection of the atherogenic potential of lipoproteins."

 

http://www.docsopinion.com/2012/11/21/the-difference-between-ldl-c-and-ldl-p/

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Motionerar du? Motion brukar ju vara ett säkert sätt att höja HDL.

Har börjat jogga för två veckor sedan men tyvärr så har jag fått ont i knät så jag har gått 4-5 km varje dag. På vinter motioncyklar jag då och då

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Trig och socker sjunker vilket tyder på att du äter färre kolhydrater

 

Att HDL minskat skulle kunna tyda på att du ännu äter för fettsnålt??

Jag äter smör och cocosolja,grädde,olivolja,rapsolja mm.Jag är nästan aldrig hungrig men har inte gått ner i vikt heller( har bara c.a 5kg övervikt) men jag har tappat fett,alla kläder sitter löst.Menar du att jag skall äta mer smör ? Tack för ditt svar.

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"Discordance

Discordance is when there is a difference between LDL-C and LDL-P. If LDL-C is high and LDL-P is low, there is discordance. If LDL-C is low and LDL-P is high, there is discordance. If both are low or both high, there is no discordance. Studies have indicated that if there is discordance between LDL-C and LDL-P, cardiovascular disease risk tracks more closely with LDL-P than LDL-C. Specifically, when a patient with low LDL-C has a level of LDL-P that is not equally low, there is higher “residual” risk. This may help explain the high number of cardiovascular events that occur in patients with normal or low levels of LDL-C.

An analysis of “Get With the Guidelines” data published in 2009 studied almost 137 thousand patients with an acute coronary event. Almost half of those had admission LDL levels <100 mg/dL (2.6 mmol/L). Thus, LDL-C does not seem to be predicting risk in these patients. However, low HDL-C and elevated TG was common among these patients. Low HDL-C and high TG is generally associated with higher LDL-P.

Among discordant patients in the Framingham Offspring Study the group with the highest risk for future cardiovascular events had high LDL-P and low LDL-C, while the group with the lowest risk had low LDL-P but higher LDL-C.

Many patients with the metabolic syndrome or type-2 diabetes have the type of discordance where LDL-P is elevated but LDL-C may be close to normal. In these individuals, measurements of LDL-C may underestimate cardiovascular risk. Measurements of ApoB or LDL-P may therefore be helpful in these individuals.

Discordance may be an important clinical phenomenon. Sometimes the question of medical therapy in primary prevention arises when there is intermediate risk, based on LDL-C. In these cases a low LDL-P level might help to confirm that the risk is indeed low, which might justify avoiding statin therapy.

Statins tend to lower LDL-C more than LDL-P. Many individuals who reach the target for LDL-C with statins, may still have raised LDL-P. This may indicate residual risk despite what is generally defined as adequate treatment."

 

"Effect of therapies

In general, most methods that lower LDL-C have some ability to lower LDL-P. However, there are some differences. Much has been written about how to lower LDL-C. Most doctors will recommend eating less fat and cholesterol from meat and dairy products. Statin therapy significantly lowers LDL-C. Therapies may affect LDL-P differently. Interventions that will lower LDL-C more than LDL-P include statins, estrogen replacement therapy, some antiretrovirals, and a low-fat, high-carbohydrate diet. Interventions that lower LDL-P more than LDL-C include fibrates, niacin, pioglitazone, omega-3 fatty acids, exercise and Mediterranean and low carbohydrate diets. Although statins lower LDL-P, they may leave a significant number of patients above the LDL-P target.

Patients with high levels of triglycerides and low HDL-C are likely to have high LDL-P despite normal or low LDL-C. Such a lipid profile is typical for individuals with the metabolic syndrome. Studies indicate that these patients may benefit most from low carbohydrate diets and that carbohydrate restriction reduces LDL-P.

LDL-P is not generally used in Europe to assess cardiovascular risk. So far, these measurements have primarily been performed in the United States. Clinical guidelines in Europe still recommend measurements of LDL-C to assess risk. Furthermore, LDL-C is still recommended to assess the effect of statin therapy. However, due to the fact that LDL-C is only a surrogate marker of the availability of atherogenic lipoproteins, its use may be of limited value. Measurements of LDL-P and ApoB are better predictors of cardiovascular risk and provide a better reflection of the atherogenic potential of lipoproteins."

 

http://www.docsopinion.com/2012/11/21/the-difference-between-ldl-c-and-ldl-p/

Inte att jag fattade mycket av detta, är inte så bra på engelska och översättningen blev knepig men tack iaf :)

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Läs hela artikeln!

 

Det handlar om.. eller som jag vill visa på att beroende på vilka mätmetoder som används så får man olika resultat av olika "behandlingsformer", men mätmetoden kan visa något helt annat!

 

Såå.. beroende på vilken lipoproteinprofil man har när man startar sin behandling/kostförändring så kan det hända lite olika saker.. på provresultatet!

 

En del kan se konstiga/sämre ut.. men mäter man med en annan metod kan man få ett helt annat resultat!

 

Eller.. de gamla värdena kan vara sämre än de nya.. beroende på vilka partiklar som var inblandade.

 

Det får du bara svar på om du mäter LDL-P eller som vi gör här i Sverige mäter APOb.. och APO-kvot.

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Jag äter smör och cocosolja,grädde,olivolja,rapsolja mm.Jag är nästan aldrig hungrig men har inte gått ner i vikt heller( har bara c.a 5kg övervikt) men jag har tappat fett,alla kläder sitter löst.Menar du att jag skall äta mer smör ? Tack för ditt svar.

Nej, du verkar ju inte fettskrämd :)

 

Prova med mer av motion fisk/skaldjur mer cocosfett o kanske mindre fröoljor

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